Table 3.
Association between H pylori infection and cancer risks
| Odds ratio (95% CI) | P-value | Adjusted odds ratio (95% CI)1 | P-value | ||
| Oral SCC vs | 1st hospital control | 0.105 (0.787-1.553) | 0.5640 | 0.961 (0.637-1.449) | 0.8494 |
| 2nd hospital control | 0.627 (0.445-0.882) | 0.0074 | 0.378 (0.190-0.751) | 0.0055 | |
| community control | 1.342 (0.952-1.891) | 0.0932 | 1.064 (0.622-1.820) | 0.8211 | |
| Esophageal SCC vs | 1st hospital control | 0.470 (0.340-0.648) | < 0.0001 | 0.454 (0.290-0.710) | 0.0005 |
| 2nd hospital control | 0.375 (0.277-0.508) | < 0.0001 | 0.315 (0.203-0.489) | < 0.0001 | |
| community control | 0.802 (0.591-1.089) | 0.1581 | 0.472 (0.257-0.865) | 0.0151 | |
| Gastric adenocarcinoma vs | 1st hospital control | 2.149 (1.465-3.152) | < 0.0001 | 2.015 (1.278-3.174) | 0.0025 |
| 2nd hospital control | 1.715 (1.187-2.479) | 0.0041 | 1.636 (1.071-2.501) | 0.0228 | |
| community control | 3.672 (2.538-5.312) | < 0.0001 | 3.060 (1.650-5.674) | 0.0004 | |
| Colon adenocarcinoma vs | 1st hospital control | 0.785 (0.549-1.123) | 0.1857 | 0.595 (0.319-1.113) | 0.1040 |
| 2nd hospital control | 0.882 (0.639-1.219) | 0.4476 | 0.851 (0.581-1.245) | 0.4055 | |
| community control | 1.888 (1.365-2.613) | 0.0001 | 1.117 (0.612-2.039) | 0.7177 | |
1
Compared to KMUH or NTUH controls: adjusting for age (continuous), gender (female vs male), educational levels (≤ primary school vs > high school; junior and high schools vs > high school), cigarette smoking (yes vs no), alcohol consumption (yes vs no) and betel nut chewing (yes vs no); Compared to community controls: Adjusting for the above factors except for betel nut chewing.