Table 4.
ELISA and/or Neutralizing Antibody Responses in Nasal Secretions of Humans to Inactivated Influenza Vaccine Given Intranasally with or without Alpha Interferon
| No. (%) ↑ to H12 |
No. (%) ↑ to H32 |
|||||||
|---|---|---|---|---|---|---|---|---|
| IFN Group1 |
No. |
EIA |
Neut |
Either |
No. |
EIA |
Neut |
Either |
| 0 | 32 | 5 (16) | 9 (28) | 11 (34) | 32 | 7 (22) | 12 (37.5) | 14 (44) |
| 1M | 30 | 4 (13) | 5 (17) | 7 (23) | 32 | 5 (16) | 6 (19) | 8 (25) |
| 10M | 30 | 5 (17) | 4 (13) | 7 (23) | 31 | 11 (35) | 9 (29) | 16 (52) |
1
Inactivated vaccine plus indicated interferon dosage (million units)
2
H1 = A/New Caledonia/20/99; H3 = A/Wisconsin/67/05