Table 1. CHARGE cohort description.
| AGES | ARIC | CHS | FHS | RS | InCHIANTI | |
|---|---|---|---|---|---|---|
| Number of individuals eligible for GWAS | 3219 | 8127 | 3275 | 3381 | 5523 | 1206 |
| Percent women | 58 | 53 | 61 | 54 | 60 | 56 |
| Mean age (yrs) | 51 (6) | 54 (6) | 72 (5) | 38 (9) | 68 (8) | 68 (16) |
| Hb (g/dL) | 13.40 (1.45) |
14.80 (1.02) |
14.11 (1.23) |
14.46 (1.37) |
14.12 (1.28) |
13.77 (1.35) |
| Hct (% ) | 40.35 (3.53) |
43.60 (2.86) |
42.14 (3.54) |
43.00 (3.9) |
41.36 ( 3.35) |
40.63 (3.49) |
| MCH (picogram) | 30.91 (1.69) |
NA | NA | 30.64 (1.85) |
30.16 (1.81) |
3.05 (1.99) |
| MCHC (%) | 33.57 (0.70) |
NA | NA | 33.67 (0.91) |
34.17 (1.15) |
33.84 (1.05) |
| MCV (femtoliter) | 92.08 (4.49) |
90.7 (4.22) |
NA | 90.7 (5.0) |
88.29 (4.30) |
90.22 (4.84) |
| RBC (1M cell/cmm) | 4.39 (0.41) |
NA | NA | 4.73 (0.46) |
4.69 (0.44) | 4.51 (0.43) |
| Years of baseline examinations | 1968-1991 | 1987-1989 | 1989-90 | 1971-1975 | 1990-1993 | 1998 |
| Years of DNA collection | 2002-2006 | 1987-1998 | 1989-1990 | 1996-1999 | 1990-1993 | 1998-2001 |
Sample sizes and summary statistics of covariates and erythrocyte traits measured in each cohort in CHARGE. Erythrocyte traits are abbreviated as: hemoglobin concentration (Hgb), hematocrit (Hct), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), mean corpuscular volume (MCV), erythrocyte count (RBC). The sample sizes presented are the range of numbers of individuals with both genotype and erythrocyte measures, after the exclusion of individuals with values beyond three standard deviations of the population mean for each erythrocyte trait.
Values for age and each erythrocyte trait are presented as mean(sd).