Table 2.
Echocardiographic characteristics of participants with normal aortic valves and aortic valve sclerosis
| Variable | Normal Aortic Valve (n = 490) | Aortic Valve Sclerosis (n = 324) | p Value |
|---|---|---|---|
| Peak aortic transvalvular velocity (m/s) | 1.3 ± 0.23 | 1.4 ± 0.25 | <0.0001 |
| Mitral annular calcium | 51 (10%) | 82 (25%) | <0.0001 |
| LV mass index (g/m2) | 95.9 ± 24.5 | 97.8 ± 24 | 0.27 |
| LV end-systolic volume index (ml/m2) | 21 ± 15.6 | 21.9 ± 17.9 | 0.47 |
| LV end-diastolic volume index (ml/m2) | 50.8 ± 18.6 | 52.1 ± 16.9 | 0.33 |
| LV ejection fraction (%) | 62 ± 10 | 62 ± 9 | 0.79 |
| LV diastolic function | |||
| Normal | 284 (66%) | 173 (60%) | 0.08 |
| Impaired relaxation | 97 (23%) | 84 (29%) | 0.05 |
| Pseudonormal | 27 (6%) | 20 (7%) | 0.74 |
| Restrictive | 22 (5%) | 13 (4%) | 0.70 |
| Left atrial volume index (ml/m2) | 32 ± 11.4 | 33.4 ± 12.6 | 0.11 |
| Isovolumic relaxation time (ms) | 116.8 ± 25.3 | 116.6 ± 25.2 | 0.91 |
| Early LV diastolic filling velocity (E wave velocity) (m/s) | 0.76 ± 0.22 | 0.76 ± 0.20 | 0.87 |
| Late (atrial) LV diastolic filling velocity (A-wave velocity) (m/s) | 0.74 ± 0.24 | 0.82 ± 0.24 | <0.0001 |
| Early/atrial LV filling ratio (E/A ratio) | 1.1 ± 0.46 | 1 ± 0.48 | 0.002 |
| Early mitral inflow deceleration time (ms) | 237.8 ± 61.1 | 244.4 ± 65 | 0.14 |
| Inducible myocardial ischemia | 93 (19%) | 88 (27%) | 0.006 |
| Post-exercise wall motion score | 1.16 ± 0.36 | 1.19 ± 0.36 | 0.25 |
Data presented as mean ± SD or number (percent).
LV = left ventricular.