Table 2. Summary statistics for the association between consumption of pickled vegetables and oesophageal cancer.
Number of studies | Q-statistica | P-valueb | I2 (%)c | Random effects OR (95% CI) | |
---|---|---|---|---|---|
All studies | 34 | 282.18 | <0.001 | 88 | 2.08 (1.66–2.60) |
After excluding the three most influential studies | 31 | 120.45 | <0.001 | 75 | 2.32 (1.92–2.81) |
Prospective studies | 3 | 10.26 | 0.006 | 81 | 1.52 (0.82–1.63) |
Case-control studies | 31 | 179.25 | <0.001 | 83 | 2.18 (1.75–2.73) |
Large studies (standard error ⩽0.5) | 30 | 259.42 | <0.001 | 89 | 2.09 (1.67–2.63) |
Studies with population-based controls | 18 | 185.63 | <0.001 | 91 | 2.11 (1.56–2.85) |
Studies with age-matched controls | 27 | 171.69 | <0.001 | 85 | 2.14 (1.66–2.76) |
Adjusted results | 24 | 196.16 | <0.001 | 88 | 2.15 (1.64–2.81) |
Studies reporting consumption rates among cases and controls | 18 | 57.61 | <0.001 | 70 | 2.55 (2.01–3.24) |
Studies from Linxian, China | 4 | 18.69 | <0.001 | 84 | 1.51 (0.98–2.33) |
Studies not from Linxian, China | 30 | 220.89 | <0.001 | 87 | 2.17 (1.70–2.78) |
Studies initiated in 1990 or earlierd | 13 | 160.43 | <0.001 | 93 | 1.73 (1.14–2.62) |
Studies initiated after 1990d | 20 | 51.69 | 0.002 | 63 | 2.28 (1.89–2.76) |
Studies from China (Mainland) | 29 | 246.64 | <0.001 | 89 | 2.10 (1.63–2.69) |
Studies not from China (Mainland) | 5 | 25.31 | <0.001 | 84 | 1.96 (1.12–3.43) |
Studies published in English literature | 15 | 198.34 | <0.001 | 93 | 2.10 (1.47–3.00) |
Studies published in Chinese literature | 19 | 60.06 | <0.001 | 70 | 2.10 (1.65–2.67) |
Abbreviations: CI=confidence interval; OR=odds ratio.
Chi-square Q-statistic for homogeneity.
P-value for the Q-statistic.
Higgins I2 statistic for heterogeneity.
One study was excluded from these analyses because the starting year was not reported.