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. 2009 Oct 13;101(10):1792–1797. doi: 10.1038/sj.bjc.6605363

Table 4. Relative risk of pancreatic cancer (RR) diagnosed in siblings of individuals affected by cancer.

  Age of diagnosis of siblings with cancer
  Any age
0–55
56–71
Sibling cancer site N RR (95% CI) N RR (95% CI) N RR (95% CI)
Upper aerodigestive tract 8 1.28 (0.64–2.57) 6 2.03 (0.91–4.53) 2 0.61 (0.15–2.45)
Oesophagus 8 3.39 (1.69–6.79) 2 3.16 (0.79–12.6) 6 3.49 (1.57–7.77)
Stomach 9 1.35 (0.70–2.59) 3 1.13 (0.36–3.50) 6 1.51 (0.68–3.37)
Colon 18 0.96 (0.60–1.53) 7 0.96 (0.46–2.01) 11 0.96 (0.53–1.74)
Rectum 13 1.09 (0.63–1.89) 3 0.69 (0.22–2.15) 10 1.32 (0.71–2.46)
Liver 11 2.07 (1.15–3.75)     10 2.88 (1.55–5.36)
Pancreas 19 3.26 (2.07–5.12) 9 5.06 (2.63–9.74) 10 2.47 (1.33–4.59)
Larynx 2 1.11 (0.28–4.46)        
Lung 25 1.09 (0.73–1.61) 13 1.74 (1.01–3.00) 12 0.77 (0.44–1.37)
Breast 88 1.19 (0.96–1.48) 59 1.37 (1.06–1.77) 29 0.95 (0.66–1.38)
Cervix uteri 7 0.79 (0.38–1.65) 6 0.79 (0.35–1.75)    
Endometrium 18 1.50 (0.95–2.39) 8 1.68 (0.84–3.36) 10 1.39 (0.75–2.59)
Ovary 11 0.95 (0.52–1.71) 9 1.26 (0.66–2.43) 2 0.45 (0.11–1.82)
Prostate 47 1.19 (0.89–1.59) 9 2.36 (1.23–4.54) 38 1.07 (0.77–1.47)
Testis 4 1.09 (0.41–2.90) 3 0.88 (0.28–2.72)    
Other male genital organs 3 3.57 (1.15–11.1) 3 6.48 (2.09–20.1)    
Kidney 11 1.17 (0.65–2.11) 8 1.86 (0.93–3.73) 3 0.59 (0.19–1.84)
Urinary organs 17 1.24 (0.77–2.00) 9 1.64 (0.85–3.16) 8 0.98 (0.49–1.96)
Melanoma 19 0.94 (0.60–1.48) 13 0.98 (0.57–1.69) 6 0.88 (0.39–1.95)
Squamous cell skin 10 1.31 (0.70–2.44) 4 1.31 (0.49–3.49) 6 1.31 (0.59–2.93)
Eye 3 3.26 (1.05–10.1) 3 4.70 (1.52–14.6)    
Nervous system 15 0.88 (0.53–1.45) 10 0.92 (0.49–1.71) 5 0.80 (0.33–1.93)
Endocrine glands 13 1.38 (0.80–2.39) 5 0.81 (0.34–1.95) 8 2.51 (1.25–5.02)
Connective tissue 9 3.12 (1.62–6.00) 5 2.70 (1.12–6.50) 4 3.87 (1.45–10.3)
Hodgkin's disease 3 1.08 (0.35–3.36) 3 1.25 (0.40–3.89)    
Non-Hodgkin's lymphoma 10 0.76 (0.41–1.41) 6 0.87 (0.39–1.95) 4 0.63 (0.24–1.69)
Leukaemia 8 0.88 (0.44–1.75) 7 1.54 (0.73–3.24)    

Bold signifies P<0.05.