Fig. 1.

Schematic diagram of significant TSP1 and TSP2 interactions in tissue repair. Interactions are shown based on their importance for each molecule independently or those verified to be shared by both TSP1 and TSP2. Molecules listed in bold are discussed in the review. All molecules are spatially oriented near the known and putative TSP domains they interact with. NH₂, amino terminus includes heparin binding site; PC, pro-collagen homology region; I, type I properdin-like repeats (TSR); II, type II EGF homology repeats; III, type III repeats include calcium binding sites; COOH, carboxy terminus