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. 2007 Feb 13;64(6):646–660. doi: 10.1007/s00018-007-6518-z

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© Birkhäuser Verlag, Basel 2007

Open Access This is an open access article distributed under the terms of the Creative Commons Attribution Noncommercial License ( https://creativecommons.org/licenses/by-nc/2.0 ), which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.

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Schematic overview of heart development in higher vertebrates. Chamber myocardium (red, ventricular; blue, atrial) expands from the outer curvatures of the primary heart tube, whereas non-chamber myocardium (gray) of the inflow tract (ift), sinus horns (sh), atrioventricular canal (avc), outflow tract (oft) and inner curvatures does not expand. Sinus horn myocardium gives rise to the sinoatrial node (san), atrioventricular canal myocardium to the atrioventricular node (avn) and atrioventricular junction. The first three panels show the left-lateral view. A, anterior; D, dorsal; P, posterior; V, ventral; a, atrium; avb, atrioventricular bundle; avc, atrioventricular canal; ev, embryonic ventricle; la, left atria; lv, left ventricle; ra, right atrium; rv, right ventricle.