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. 2009 Dec 1;136(23):3959–3967. doi: 10.1242/dev.039768

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Fig. 6. — Gene expression analysis of dUE-rescued Shh^-/- GTs. (A-G″) Mouse embryos were treated with Tm at E9.5 and collected on E11.5 for in situ hybridization with the probes indicated. The expected expression pattern of Fgf8, Bmp7, Msx2 and Wnt5a was observed in the controls (A-D), was absent in Shh^-/- GTs (A′-D′), but was fully (A″,B″, arrows) or partially (C″,D″, arrows) restored in dUE-rescued Shh^-/- GTs. Expression of Hoxd13 and Hoxa13 was either severely reduced (E′,F′) or undetectable (E″,F″) in both Shh^-/- and dUE-rescued Shh^-/- GTs. Ptch1 expression was not detected in either Shh^-/- or dUE-rescued GTs (G-G″).