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. Author manuscript; available in PMC: 2010 Sep 25.
Published in final edited form as: Chem Biol. 2009 Sep 25;16(9):961–970. doi: 10.1016/j.chembiol.2009.09.001

Figure 4. Model of the LasR-TP-5 interaction.

Figure 4

Stereo-view of a model structure of the LasR-TP-5 complex derived from the experimentally determined structure of the LasR-TP-3 complex. The protein residues are shown in yellow and the TP-5 ligand is shown in cyan. A van der Waals surface for the ligand is superimposed and shown as pink dots. Note the steric clash between the backbone carbonyl of Leu-125 and a chlorine atom on the TP-5 ring.