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Empirical Bayesian stimates (EBEs) of CL (panel A), V1 (panel B), ETA1(CL) for base model (panel C) and ETA1(CL) for final model (panel D); ETA2(V1) for base model (panel E), and ETA2(V1) for final model (panel F) versus Sex. V 1 volume of distribution in the central compartment, CL clearance, ETA2(V 1) random effect of V1, ETA1(CL) random effect of clearance
