Table 3.
Early MVO | ||||
---|---|---|---|---|
Absent | Present | |||
Disappearance late MVO (−) | Persistence late MVO (+) | |||
(n = 31) | (n = 8) | (n = 45) | p value | |
Age (years) | 61 ± 9 | 61 ± 10 | 59 ± 13 | 0.8 |
Male sex | 22 (71) | 5 (63) | 34 (76) | 0.7 |
BMI | 27 ± 4 | 26 ± 2 | 27 ± 4 | 0.7 |
Smoking | 26 (84) | 7 (88) | 41 (91) | 0.6 |
Hypercholesterolaemia | 8 (35) | 2 (29) | 13 (37) | 0.9 |
Diabetes | 3 (10) | 0 | 2 (4) | 0.4 |
Previous angina pectoris | 11 (36) | 2 (25) | 20 (44) | 0.5 |
Anterior localisation of MI | 7 (23) | 1 (13) | 19 (42) | 0.08 |
Three-vessel disease* | 8 (26) | 1 (13) | 12 (27) | 0.7 |
Thrombosuction | 9 (29) | 2 (25) | 15 (33) | 0.9 |
Time to balloon inflation (min) | 232 ± 96 | 196 ± 80 | 215 ± 80 | 0.6 |
Adenosine or nitroglycerine i.c. | 21 (68) | 5 (63) | 31 (69) | 0.9 |
Abciximab downstream | 12 (39) | 5 (63) | 26 (58) | 0.2 |
Final TIMI 3 flow | 27 (90) | 5 (71) | 41 (91) | 0.3 |
Total CK (AUC, 1,000 h units l−1) | 30 ± 31a | 39 ± 14b | 73 ± 32a, b | <0.001a/0.01b |
Baseline CMR | ||||
LVEDVi (ml/m2) | 81 ± 14 | 87 ± 17 | 86 ± 17 | 0.4 |
LVEF (%) | 56 ± 7c | 54 ± 6 | 48 ± 7c | <0.001c |
Infarct size (% LV) | 6 ± 8d | 12 ± 4e | 23 ± 9d,e | <0.001d/0.003e |
Early MVO size (% of LV) | 0f | 0.8 ± 0.4 | 5 ± 3.1f | <0.001f |
Follow-up CMR | ||||
LVEDVi (ml/m2) | 76 ± 17 | 85 ± 16 | 84 ± 20 | 0.2 |
LVEF (%) | 59 ± 6g | 55 ± 4 | 51 ± 7g | <0.001g |
Values are presented as number of patients with percentages in parentheses or mean ± standard deviation
Abbreviations: BMI body mass index, i.c. intracoronary, AUC area under the curve, LVEDVi left ventricular end-diastolic volume index, LVESVi left ventricular end-systolic volume index, LVSVi left ventricular stroke volume index, LVEF left ventricular ejection fraction, LVMi left ventricular mass index, LE late enhancement, MVO microvascular obstruction
*Stenosis greater than 70%
a,c,d,f,gFor the difference between absence of MVO (early and late) and persistence of late MVO
b,eFor the difference between disappearance and persistence of late MVO