Table 3.
Effect of interaction between aspirin and selected risk factors
| Factors | Aspirin in previous fortnight
|
Adjusted odds ratios (95% CI)* | P value | |
|---|---|---|---|---|
| No (%) of cases | No (%) of controls | |||
| Hypertension:† | ||||
| Hypertensive | 26/160 (16) | 26/116 (22) | 0.53 (0.25 to 1.14) | 0.028 |
| Normotensive | 29/135 (21) | 32/206 (16) | 1.62 (0.83 to 3.14) | |
| High cholesterol concentration:† | ||||
| High cholesterol concentration | 10/43 (23) | 12/72 (17) | 2.62 (0.80 to 8.57) | 0.077 |
| Not advised of high cholesterol concentration | 44/256 (17) | 45/249 (18) | 0.81 (0.47 to 1.42) | |
| Cardiovascular disease history:† | ||||
| Yes | 11/29 (38) | 15/49 (31) | 0.98 (0.32 to 3.03) | 0.967 |
| No | 43/266 (16) | 43/271 (16) | 1.01 (0.58 to 1.75) | |
| Smoking status:† | ||||
| Current smoker | 12/75 (16) | 10/68 (15) | 1.33 (0.36 to 4.94) | 0.896 |
| Never smoker | 24/128 (19) | 24/135 (18) | 0.93 (0.43 to 1.98) | |
| Former smoker | 19/97 (20) | 24/119 (20) | 1.01 (0.47 to 2.17) | |
| Alcohol intake:† | ||||
| Current drinker | 36/205 (18) | 45/233 (19) | 0.85 (0.47 to 1.51) | 0.391 |
| Never drinker | 12/65 (18) | 8/64 (13) | 1.87 (0.52 to 6.67) | |
| Former drinker | 7/30 (23) | 5/25 (20) | 1.92 (0.40 to 9.38) | |
| Sex:† | ||||
| Female | 20/120 (17) | 21/123 (17) | 1.01 (0.47 to 2.17) | 0.981 |
| Male | 35/180 (19) | 37/199 (19) | 1.00 (0.51 to 1.96) | |
| Age: | ||||
| Increases for each year of age | — | — | 1.04 (0.997 to 1.09) | 0.051 |
*
Multivariate analyses adjusted for hypertension, serum cholesterol concentration, diabetes, previous cardiovascular disease, body mass index, exercise, alcohol intake, and smoking.
†
Aspirin use in previous fortnight versus no use in previous fornight for each analysis.