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. Author manuscript; available in PMC: 2009 Dec 1.
Published in final edited form as: Cell Motil Cytoskeleton. 2008 Sep 18;65(12):955–963. doi: 10.1002/cm.20318

Fig. 1. Relative function of native and “trans” β-tubulin configurations in Drosophila spermatogenesis.

Fig. 1

Portions of microtubule protofilaments are shown schematically. Co-assembly of β1 plus β2 supports nearly normal function of all categories of microtubules in spermatogenesis, whereas the combination of the paired reciprocal chimeric β-tubulins, β1β2C plus β2β1C, is poorly functional. Co-assembled heterodimers containing different β-tubulin species are shown uniformly distributed in a microtubule protofilament for simplicity. However, the in vivo situation would most likely represent random representation of co-assembled species in the microtubule polymer.