Table 4. Mean and 95% confidence interval for each CITT outcome measure, by treatment group and time.
Outcome / | HBPP | HBCVAT+ | OBVAT | OBPT | ||||
---|---|---|---|---|---|---|---|---|
Time | Mean | 95% CI | Mean | 95% CI | Mean | 95% CI | Mean | 95% CI |
CI Symptom Survey score | ||||||||
At Baseline | 27.8 | 25.8, 29.8 | 31.7 | 29.3, 34.1 | 30.2 | 27.7, 32.7 | 29.8 | 27.4, 32.2 |
At Week 12 | ||||||||
Unadjusted | 21.3 | 18.0, 24.6 | 24.7 | 21.9, 27.5 | 15.1 | 12.6, 17.6 | 21.9 | 18.8, 25.0 |
Adjusteda | 22.9 | 20.4, 25.5 | 23.5 | 20.9, 26.0 | 15.0 | 12.6, 17.4 | 21.9 | 19.3, 24.4 |
Total Changea | -7.1 | -9.6, -4.5 | -6.0 | -8.6, -3.4 | -14.8 | -17.2, -12.4 | -7.8 | -10.4, -5.3 |
Near point of convergence break (cm) | ||||||||
At Baseline | 14.7 | 12.5, 16.9 | 14.4 | 12.4, 16.4 | 13.3 | 11.6, 15.0 | 14.4 | 12.3, 16.5 |
At Week 12 | ||||||||
Unadjusted | 8.0 | 6.1, 9.9 | 6.8 | 5.2, 8.4 | 3.5 | 3.0, 4.0 | 10.3 | 8.4, 12.2 |
Adjusteda | 7.8 | 6.4, 9.2 | 6.8 | 5.4, 8.2 | 4.0 | 2.7, 5.3 | 10.3 | 8.9, 11.6 |
Total Changea | -6.4 | -7.8, -5.0 | -7.5 | -8.9, -6.1 | -10.4 | -11.7, -9.0 | -3.9 | -5.3, -2.5 |
Positive fusional vergence blur or break (Δ)b | ||||||||
At Baseline | 11.3 | 10.2, 12.4 | 10.5 | 9.4, 11.6 | 11.0 | 9.9, 12.1 | 11.0 | 10.2, 11.8 |
At Week 12 | ||||||||
Unadjusted | 19.1 | 16.8, 21.4 | 22.8 | 19.8, 25.8 | 30.7 | 27.5, 33.9 | 17.8 | 15.5, 20.1 |
Adjusteda | 18.9 | 16.2, 21.6 | 23.0 | 20.3, 25.7 | 30.5 | 28.0, 33.1 | 17.8 | 15.2, 20.5 |
Total Changea | 7.9 | 5.2, 10.6 | 12.0 | 9.3, 14.8 | 19.7 | 17.1, 22.3 | 6.9 | 4.2, 9.5 |
HBPP: Home-based pencil push-up therapy
HBCVAT+: Home-based computer vergence/accommodative therapy and pencil push-ups
OBVAT: Office-based vergence/accommodative therapy with home reinforcement
OBPT: Office-based placebo therapy with home reinforcement
CI: Confidence Interval
Total Change: Week 12 minus baseline
Adjusted for measurement obtained at the baseline examination
The blur finding was used, but if the patient did not report a blur, the break finding was used