Table 2.
Absolute and relative risk for high risk findings at third exam based on findings from two prior examinationsa
| Adenoma Findings @ baseline | Adenoma Findings @ 2nd exam | Mean follow up time (mos) 2nd–3rd exam (SD) | n (%) in strata (a) |
n with high risk findings on 3rd exam (b) |
Absolute risk (95% CI) for advanced or multiple on 3rd exam (c=b/a) |
Number Needed to Scope to identify clinically significant findings on 3rd exam (d=1/c) |
|---|---|---|---|---|---|---|
| High Risk | High Risk | 42 (16) | 44 (7.8) | 8 | 18.2% (8.2, 32.7) |
5.5 |
| High Risk | Low Risk | 44 (13) | 59(10.5) | 8 | 13.6% (6.0, 25.0) |
7.4 |
| High Risk | No adenomas | 51 (13) | 122(21.6) | 15 | 12.3% (7.0, 19.5) |
8.1 |
| Low Risk | High Risk | 37 (13) | 40(7.1) | 8 | 20.0% (9.0, 35.6) |
5 |
| Low Risk | Low Risk | 44 (12) | 95(16.8) | 9 | 9.5% (4.4, 17.2) |
10 |
| Low Risk | No adenomas | 51 (14) | 204(36.2) | 10 | 4.9% (2.4, 8.8) |
20.4 |
a
The risk difference between those with no adenomas at 2nd exam and high risk vs low risk findings at baseline was 0.07 (95% CI 0.01, 0.14)
The risk difference between those with low risk adenomas at 2nd exam and high risk vs low risk findings at baseline was 0.04 (95% CI −0.06, 0.15)
The risk difference between those with high risk adenomas at 2nd exam and high risk vs low risk findings at baseline was −0.02 (95% CI −0.19, 0.15)