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. Author manuscript; available in PMC: 2010 Apr 15.
Published in final edited form as: J Cell Biochem. 2009 Apr 15;106(6):992–998. doi: 10.1002/jcb.22078

Fig. 2. Targeted therapy of experimental lymph node metastasis with S. typhimurium A1-R.

Fig. 2

(A) Scheme for experimental lymph node metastasis model. Cancer cells were injected into the inguinal lymph node. After injection, the cells trafficked to the axillary lymph node and formed metastases. Small skin incisions were made around both the inguinal lymph node and axillary lymph node for purposes of imaging. (B) Seven days after XPA1-RFP human pancreas cancer cell injection in the inguinal lymph node, an experimental metastasis was observed in axillary lymph node. After A1-R was injected in the inguinal lymph node, bacteria were imaged around the tumor in the axillary lymph node. (C) Seven days after bacteria injection, the metastasis has been eradicated.