Figure 3.

Tertiary structure of AChBP and projection of GlyR α subunit associated structural determinants. Positions of the glycine (yellow) binding pocket, formed by amino acids GY and KYT (C-loop), of the disulfide bridge between β-sheets 6’ and 7 as well as of proline residues at positions 185 (α1 and α3) and 192 (α2) are shown. N- and C-termini and the location of the chloride channel pore are indicated. β-sheets, α-helices and coils are color-coded (green, red and black, respectively). GlyR sequence was projected on the structure view of AChBP downloaded from www.pdb.org. The position of β-sheets served as reference points.