Table 1.
Patient Characteristics
| Characteristic | All patients (n=21) | % |
|---|---|---|
| Median Age, years (range) | 63 (48–80) | |
| Male:Female | 14:7 | |
| Caucasian | 20 | 95 |
| African American | 1 | 5 |
| Median time in months from diagnosis(range) | 100.6 (31.3–187.5) | |
| Median Number of prior therapies (range) | 5 (1–13) | |
| Refractory to last therapy | 13 | 62 |
| Prior fludarabine | 21 | 100 |
| Fludarabine refractory | 7 | 33 |
| Rai Stage | ||
| Missing | 1 | 5 |
| 3 | 3 | 14 |
| 4 | 17 | 81 |
| Adenopathy | ||
| ≥ 5 cm | 4 | 19 |
| ≥ 10 cm | 0 | 0 |
| Splenomegaly | 7 | 33 |
| Blood | ||
| WBC (109/l) | ||
| Median | 30.6 | |
| Range | 1.1–347.8 | |
| Absolute lymphocyte count (109/l) | ||
| Median | 27.5 | |
| Range | 0.41–331 | |
| Hemoglobin (g/l) | ||
| Median | 101 | |
| Range | 79–151 | |
| Platelets (109/l) | ||
| Median | 49 | |
| Range | 10–220 | |
| Cytogenetic abnormalities | ||
| None | 1 | 5 |
| del(13q) | 2 | 10 |
| del(11q22.3) | 9 | 43 |
| del(17p13.1) | 9 | 43 |
| Complex | 2 | 10 |
| Diploid | 1 | 5 |