Fig. 4.
Effect of CRMP-2 on DRG Cav2.2 activation. (A) Normalized conductance (G) versus voltage for DRG neurons transfected with EGFP or CRMP-2–EGFP. Values are mean ± s.e.m. and most error bars are smaller than the symbols. (B) Plots of activation time constants (τactivation) were calculated from single exponential fits to the falling phase of the voltage-activated inward current. The mean activation time constants for CRMP-2–EGFP currents were significantly faster than those for EGFP (P<0.05, Student's t-test).