Table 1.
Hemodynamic parameters (heart rate, blood pressure), work capacity (Watts) and Tissue Doppler echocardiography variables (expressed as the average of the four LV walls) measured at baseline and maximal work loud during adenosine and placebo infusions
Adenosine | Placebo | |||
---|---|---|---|---|
Variables | Baseline | Peak | Baseline | Peak |
Heart rate, bpm | 59 ± 11 | 104 ± 13* | 62 ± 14 | 106 ± 13* |
SBP, mm Hg | 143 ± 12 | 172 ± 18* | 148 ± 20 | 169 ± 28* |
Watts | 00.0 ± 0.0 | 83 ± 19 | 00.0 ± 0.0 | 83 ± 28 |
ST depression | 1.8 ± 1.4 | 1.4 ± 1.0 | ||
PSV, cm/s | 5.5 ± 1.6 | 6.4 ± 3.2* | 5.5 ± 1.6 | 7.6 ± 2.6* |
A-V plane, mm | 9.6 ± 2.7 | 10.9 ± 4.4* | 9.0 ± 2.6 | 11.7 ± 4.3* |
S% | 17.4 ± 5.1 | 23.4 ± 7.4* | 16.5 ± 3.8 | 22.1 ± 7.2* |
SR-1 | -0.9 ± 0.3 | -1.9 ± 0.5* | -1.0 ± 0.2 | -1.9 ± 1.5* |
E'-wave, cm/s | 6.5 ± 1.9 | 8.8 ± 4.0* | 5.5 ± 2.3 | 8.5 ± 4.2* |
A'-wave, cm/s | 4.9 ± 2.4 | 5.1 ± 3.6 | 4.9 ± 2.5 | 4.1 ± 2.9 |
Values are expressed as means ± SD.
Abbreviations: A' = late diastolic A-wave; A-V = atrio-ventricular plane displacement; bpm = beats per minute; E' = early diastolic E-wave; PSV = peak systolic velocity; SBP = systolic blood pressure, S% = strain; SR = strain rate.
* P < 0.01 Peak versus baseline