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. 2009 Nov 2;187(3):429–442. doi: 10.1083/jcb.200904049

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© 2009 Brunelle et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jcb.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

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Figure 6. — Higher BIM and PUMA expression observed in MCL-1– and BCL-2–overexpressing leukemias. Western blot comparing protein levels among three Eμ-Myc tumors, two BCL-2/Eμ-Myc leukemias, and three Mcl-1/Eμ-Myc leukemias. (A) The proteins blotted were MCL-1, BCL-2, BIM, PUMA, BID, BAD, BAX, and BAK. Please note that the BCL-2 transgene in the BCL-2/EμMyc lymphomas is human. (B) The proteins blotted were BAD, Phospho-Bad (Ser112), and Actin.