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Ad.hTRAIL therapy significantly suppresses the growth of established tumors. Male SCID mice were injected subcutaneously with 1×106 U87MG cells. Animals were then given an injection of Ad.lacZ or Ad.hTRAIL at the site of tumor implantation on day 7. Tumor volume (µL) was monitored every other day for 30 days. Animals treated with Ad.hTRAIL have significantly smaller tumors than Ad.lacZ-treated animals (*p<0.05).
