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| Species | Unclear | No | Yes | Yes (%) |
| Mouse (n = 36) † | 0 | 11 | 25 | 69 |
| Primate (n = 26) † | 0 | 12 | 14 | 54 |
| Rat (n = 59) † | 0 | 23 | 36 | 61 |
| All (n = 121) † | 0 | 46 | 75 | 62 |
Number of studies that used two or more design factors.
Overall 62% (75/121) of all studies that had two or more design factors reported using a factorial design.
