Table 5.

Sensitivity, specificity, PPV, and NPV for serum amylase, P-isoamylase, and lipase assays

	Author	Year	Methodology	Upper normal limit (IU/l)	Cutoff value (IU/l)	Sensitivity	Spencificity	PPV	NPV
Amylase	Pace16	1985	Phadebas	300	300	100.0	71.6	15.6	100
	Steinberg17	1985	Phadebas	326	326	94.9	86.0	75.5	97.4
					600	92.3	100.0	100.0	96.6
	Ventrucci18	1986	Phadebas	377	377	91.7	77.8	35.5	98.6
	Thomson10	1987	Phadebas	316	316	95.6	97.6	91.7	98.8
					1000	60.9	100.0	100.0	90.4
P-amylase	Koehler19	1982	Cellulose electrophoresis	52	52	84.2	38.8	59.3	70.0
	Steinberg17	1985	Wheat protein inhibitor	181	181	92.3	85.1	73.5	96.1
					375	84.0	96.5	91.7	93.3
	Pace16	1985	Cellulose electrophoresis	120	225	100.0	48.9	17.9	100.0
	Ventrucci18	1986	Phadebas	220	220	100.0	84.4	46.2	100.0
Lipase	Steinberg17	1985	Turbidimetric	72	75	86.5	99.0	97.0	95.1
	Ventrucci18	1986	ELISA	62	62	91.7	84.7	42.3	98.9
	Thomson10	1987	Seragen-lipase	68	68	100.0	96.0	85.0	100.0

PPV, positive predictive value; NPV, negative value Adapted from Agarwal et al.⁹