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. Author manuscript; available in PMC: 2010 Apr 1.
Published in final edited form as: Nat Struct Mol Biol. 2009 Sep 6;16(10):1056–1062. doi: 10.1038/nsmb.1655

Fig. 2. Predicted and observed nucleosome distribution patterns on bacteriophage λ-DNA.

Fig. 2

The nucleosome distributions predicted by the Segal et al.6 (magenta) and the Field et al.14 (green) models for λ-DNA are shown in (a). The AT-content of the λ is shown (blue line; calculated with a 100-bp window) superimposed with the distribution of poly(dA–dT) tracts ≥5-mers (gray bars), which are asymmetrically distributed and comprise 3.2% of the phage genome. The observed nucleosome distribution is shown in the lower panel, and is comprised of data from both canonical nucleosomes and nucleosomes bearing H2AZ (Supplementary Fig. 7). The theoretical data is shown at 1-bp resolution, and the observed data is compiled into 758-bp bins. Supplementary Fig. 4 shows examples where the predicted locations are binned to the same resolution as the experimental data. Panel (b) shows Pearson correlation analysis of the poly(dA–dT) distribution and the observed nucleosome distribution compared to the theoretical predictions.