Skip to main content
. 2009 Nov 30;4(11):e8075. doi: 10.1371/journal.pone.0008075

Figure 2. The LSL-KrasG12D; Trp53Flox/Flox mouse model of soft tissue sarcoma provides insight into human MFH.

Figure 2

A, An oncogenic Ras signature is enriched in human MFH samples compared to other types of soft tissue sarcoma (p = 0.002, non-parametric Mann-Whitney test). B, Q-RT-PCR for Foxm1 in murine soft tissue sarcomas correlates with metastatic potential of primary tumors (p = 0.01, two-tailed student's T-test, scale bars represent one standard deviation). C, FOXM1 expression in a tissue microarray correlates with metastasis free survival in human MFH (p = 0.038).