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. Author manuscript; available in PMC: 2010 Nov 2.
Published in final edited form as: DNA Repair (Amst). 2009 Sep 10;8(11):1283–1289. doi: 10.1016/j.dnarep.2009.08.002

Figure 5. Putative interactions of guanine and thymine with CacOgg at the estranged base binding site.

Figure 5

The figure shows the putative interactions that CacOgg may make with G (red) or T (green) as the estranged base. The putative H-bonds are depicted in the same color as their corresponding model. Asn127 most likely performs a 180° rotation around its Cγ to interact with the O4 acceptor of thymine. In both models, the estranged base stacks against of Phe179. The hydrophilic interactions are extrapolated from the CacOgg/8-oxoG:C and/8-oxoG:A complexes.