Figure 7. Most significantly enriched (p = 10−29) network of S. mansoni genes that were sustainably altered at 1h and 24h treatment with human TNF-alpha.
In red are the genes that were induced in 1 h and 24 h with respect to their control. In green are genes that were repressed in 1 h and 24 h with respect to their control. Non-significantly altered genes are in grey; in white are the human genes known to belong to the network for which no homolog was found in S. mansoni. MIR124 stands for human microRNA 124. Direct relations are marked by continuous lines, while indirect relations have dashed lines.