TABLE 1.
Clinical Characteristics and Histology Diagnosis
| Patient Age |
Race and Ethnicity |
||||||
|---|---|---|---|---|---|---|---|
| Age | n=403 (%)* | n=122 (%)** | n=403 (%)* | ||||
| HPV (HC2) | Race | Ethnicity | |||||
| HPV (+) | HPV (−) | White | 268 (67) | Hispanic | 99 (25) | ||
| <=30 | 64 (16) | 8 (6.5) | 8 (6.5) | African American | 48 (12) | ||
| 31–40 | 102 (25) | 23 (19) | 13 (11) | Asian | 8 (2) | Non-Hispanic | 287 (71) |
| 41–50 | 115 (29) | 9 (7) | 31 (25) | American Indian | 1 | ||
| 51–60 | 72 (18) | 7 (6) | 15 (12) | Not-Specified | 78 (19) | Not-Specified | 17 (4) |
| 61–70 | 37 (9) | 1 (1) | 6 (5) | ||||
| >=71 | 13 (3) | 0 | 1 (1) | ||||
| Histologic Diagnosis n=403 (%)* | |||||
| Insignificant Cervical Lesions | Significant Cervical Lesions | ||||
| 292 (72) | 111 (28) | ||||
| Negative/Benign | 232 | Squamous Lesions | 74 (67) | Glandular Lesions. | 37 (33) |
| Negative, NOS | 156 | CIN2 | 14 | AdenoCa. In Situ | 23 |
| Metaplasia, NOS | 19 | Invasive AdenoCa. | 14 | ||
| Squamous Metaplasia | 53 | CIN3 | 58 | Adenoca. NOS | 7 |
| Immature Squamous Metaplasia | 4 | Endometrioid | 1 | ||
| Atypia† | 23 | Squamous cell Ca. | 2 | Clear cell | 1 |
| Glandular Hyperplasia | 5 | Small cell | 1 | ||
| CIN1/Mild Dysplasia | 32 | Adenosquamous | 2 | ||
| Villoglandular | 1 | ||||
| Serous | 1 | ||||
*
403 cases were tested for CA-IX expression.
**
Among 403 cases, 122 were tested for high-risk HPV. NOS: not otherwise specified;
†
including glandular and squamous lesions in which cellular atypia falls short of AIS and CIN1.
CIN2: moderate dysplasia; CIN3: severe dysplasia/in situ squamous cell carcinoma.