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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: J Acquir Immune Defic Syndr. 2009 Jul 1;51(3):264–267. doi: 10.1097/QAI.0b013e3181aa12f2

Table 1. Concentration and Antigen Binding Capacity of IgA and IgG in Flash-heated and Unheated Breastmilk from HIV-Positive Mothers (n=50).

Immunoglobulin Unheated
Median
Concentration
(range)		 Flash-heated
Median
Concentration
(range)		 Unheated
Geometric
Mean
(sd)		 Flash-
heated
Geometric
Mean
(sd)		 p-value
Paired t-
test		 % of
Concentration in
Unheated Milk
Detected Post-
heat
Total IgA
(ug/ml)		 378.2
(155.6, 13164.5)		 323.5
(118.5, 7027.2)		 398.2
(1.9)		 318.0
(1.9)		 <.001 79.9
Total IgG
(ug/ml)		 117.2
(23.8, 7306.3)		 82.8
(15.6, 6953.5)		 133.3
(2.5)		 89.1
(2.7)		 <.001 66.9
HIV-1 gp120 IgG
(ng/ml)		 1174.4
(20.1, 126413.2)		 957.5
(21.6, 70010.6)		 1118.0
(3.9)		 827.6
(3.8)		 <.001 74.0
Influenza virus IgG
(ng/ml)		 246.0
(38.4, 3697.5)		 284.2
(79.6, 3916.5)		 240.8
(2.2)		 272.3
(1.9)		 0.025 113.1
Influenza virus IgA
(ng/ml)		 465.7
(93.2, 5496.5)		 610.6
(247.1, 4999.5)		 575.6
(2.3)		 663.8
(1.9)		 0.029 115.3
Pneumococcal polysaccharide IgA
(ng/ml)		 797.3
(289.8, 32198.9)		 608.7
(71.0, 38209.2)		 906.5
(2.1)		 635.7
(2.4)		 <.001 70.1
Salmonella lipopolysaccharide IgA
(ng/ml)		 270.8
(101.1, 5546.7)		 253.5
(65.2, 4996.3)		 284.0
(1.9)		 308.7
(2.0)		 0.13 108.7
Poliovirus IgA
(ng/ml)		 729.3
(138.9, 11336.2)		 525.5
(94.5, 10508.5)		 914.8
(2.6)		 604.2
(2.6)		 <.001 66.1