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. Author manuscript; available in PMC: 2010 Sep 1.
Published in final edited form as: J Mol Cell Cardiol. 2009 Jun 21;47(3):400–410. doi: 10.1016/j.yjmcc.2009.06.010

Figure 3. ATP-induced nuclear translocation of NFATc1 is sensitive to La3+ and extracellular Ca2+.

Figure 3

A: Pharmacological inhibition of CCE by La3+ ions. TG-induced CCE (control, left trace) was blocked in the presence of La3+-ions in the extracellular solution (right trace). B: Representative recordings of ATP-induced Ca2+ transients showed that La3+ or the absence of extracellular Ca2+ prevented the sustained component of the Ca2+ transient (CCE). C: Summary data: Nuclear translocation of NFATc1-GFP in response to ATP was suppressed by La3+ ions. *, statistically significant (P < 0.05) compared to control.