Table 1. Mature and Immature Vessels in RA, OA or Normal Synovial Tissues.
RA n = 82 | OA n = 14 | Normal n = 4 | p-value* | |
CD31+/aSMA+ Vessels/mm2 | 294±95 | 74±28 | 94±44 | <0.0001 |
CD31+/aSMA– Vessels/mm2 | 26±27 | 0.6±1.2 | 0±0 | <0.0001 |
Total Vessels/mm2 | 319±98 | 74.5±28 | 94±44 | <0.0001 |
Proportion of tissues with CD31+/aSMA– vessels (%) | 66/82(80%) | 3/14(21%) | 0/4(0%) | <0.0001 |
CD31+/aSMA+: Mature vessels; CD31+/aSMA–: Immature vessels; Total vessels represents the sum of both mature and immature vessels.
(*) RA versus OA.