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. Author manuscript; available in PMC: 2010 Oct 20.
Published in final edited form as: Biochemistry. 2009 Oct 20;48(41):9801–9809. doi: 10.1021/bi901024m

Table 1.

Reduction Potentials of Mutant DHODs

Enzyme Reduction Potentiala
Wild-Typeb −229 mV
Ser175Ala −267 mV
Thr178Ser −249 mV
Thr178Ala −269 mV
Thr178Val −264 mV
Phe115Ala −229 mV
Phe115Leu −245 mV
Phe115Trp −258 mV
Phe115Leu/Thr178Val −239 mV
a

Reduction potentials determined by the xanthine/xanthine method have a precision of ± 5 mV.

b

Data taken from (18).