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. Author manuscript; available in PMC: 2010 Sep 29.
Published in final edited form as: Circulation. 2009 Sep 14;120(13):1255–1265. doi: 10.1161/CIRCULATIONAHA.109.873695

Table 3. Quantitation of Elastase-digested fibrin degradation products in plasma samples.

TGN was induced in WT or Mac-1-/- mice and plasma from mice at the indicated times following TGN were examined for NE activity by examining fibrin degradation products reported to be specifically generated by granulocyte-elastase (e-XDP).

Day 0 1 2 4
Wild-type
(μg/ml)
0.06 ± 0.06
(n=4)
2.26 ± 0.17
(n=12)
1.69 ± 0.19
(n=5)
1.97 ± 0.28
(n=4)
Mac-1-/-
(μg/ml)
0.01 ± 0.01
(n=4)
1.68 ± 0.16
(n=12)
1.04 ± 0.29
(n=4)
2.30 ± 0.67
(n=4)
p value 0.40 0.02 0.09 0.66