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Linear correlation coefficients and P values for the statistical analysis of the relationship between the clogP and the Ki values for hiCE inhibition by the sulfonamides. Results are presented using either 1 or 3 as substrates.
| Substrate | Parameter | ||
|---|---|---|---|
| r2 | Spearman r | P | |
| 1 | 0.486 | −0.832 | <0.0001 |
| 3 | 0.432 | −0.615 | <0.0001 |
