Table IV.

White matter tract regions exhibiting significant difference in FA in patients with poorer motor skill compared to controls

WM region	Tract(s)	Cluster size (mm3)	Max P, 10−x	MNI coordinates (mm)			Diffusivity
				X	Y	Z	Axial	Radial
Lesion zone
Patients < controls
IL precentral gyrusa	CST and SLF	1,244	5.7	−22	−5	36		↑b
Anterior/superior corona radiata	CST and SLF
Genu IC	Corticobulbar tract
Anterior limb IC	Anterior thalamic radiation and frontopontine fibers
IL precentral gyrus	CST and SLF	88	3.5	−45	−8	35		↑b
IL superior corona radiata	SLF	152	2.6	−41	−18	29
IL superior corona radiata	SLF	75	2.3	−37	−33	35	↓b	↑c
IL external/extreme capsule	Corticostriate fibers and temporo‐parieto‐frontal fibers	324	5.7	−30	13	2		↑c
Remote from lesion
Patients < controls
IL PLIC, cerebral peduncle	CST	645	4.8	−18	−7	3		↑d
Genu IC	Corticobulbar tract
Anterior limb ICa	Anterior thalamic radiation and frontopontine fibers
IL ventral pons	CST	152	2.7	−10	−21	−26		↑d
IL dorsal pons	Pontocerebellar fibers	145	4.1	−7	−38	−45		↑c
IL anterior/superior corona radiataa	CST and SLF	292	4.2	−28	1	30		↑b
IL external/extreme capsule	Corticostriate fibers and temporo‐parieto‐frontal fibers	273	6.2	−28	18	2		↑d
IL internal capsule, retrolenticular part	Inferior longitudinal fasciculus	173	2.8	−38	−34	0		↑d
CL PLIC, cerebral pedunclea	CST	563	4.8	24	−5	8		↑c

^aRegion shown in Figure 2A.

^b P < 0.05 patients versus controls, unpaired t‐test.

^c P < 0.01.

^d P < 0.001.