Table 1.
Comparison of biochemical parameters before and after treatment with spironolactone in 27 women with hirsutism
| Parameter† | Normal range | Before treatment | After treatment |
|---|---|---|---|
| FBS (mg dl−1) | 76–109 mg dl−1 | 86.5 ± 19.9 | 79.1 ± 9.1 |
| TG | <150 mg dl−1 | 81.8 ± 31.6 | 83.8 ± 38.5 |
| TC | <200 mg dl−1 | 188.9 ± 38.3 | 199.8 ± 33.7 |
| HDL (mg dl−1)* | >35 mg dl−1 | 39.5 ± 10.3 | 32.2 ± 7.9 |
| LDL (mg dl−1)* | <130 mg dl−1 | 133.1 ± 34.2 | 150.8 ± 31.0 |
| TC/HDL* | <5 | 5.0 ± 1.5 | 6.4 ± 1.9 |
| Testosterone* | 0.2–0.9 ng ml−1 | 0.87 ± 0.5 | 0.70 ± 0.4 |
| DHEAS* | 65–380 µg dl−1 | 327.1 ± 145.5 | 238.5 ± 143.6 |
| PRL* | <400 mU l−1 | 349.6 ± 166.3 | 267.0 ± 172.8 |
*
Significant difference (P < 0.05) before and after treatment.
†
Values are expressed as mean ± SD. FBS, fasting blood sugar; HDL, high-density lipoprotein; LDL, low-density lipoprotein; PRL, prolactin; TC, total cholesterol; TG, triglyceride; DHEAS, dehydroepiandrosterone sulphate.