Table 1.
Iron load measures and corresponding serum ferritin levels
Iron load | Patients, n | Serum ferritin, ng/mL |
||||
---|---|---|---|---|---|---|
Mean | (SD) | Median | Minimum | Maximum | ||
Pretransfusion | 95 | 139 | (126) | 97 | 10 | 628 |
TIL, mg/kg | ||||||
50 | 26 | 914 | (581) | 838 | 29 | 2549 |
150 | 20 | 2066 | (762) | 1996 | 1019 | 4401 |
250 | 9 | 2259 | (991) | 2165 | 173 | 3669 |
350 | 3 | 2697 | (912) | 2816 | 1732 | 3544 |
LIC, mg/g dw | ||||||
5 | 13 | 1889 | (980) | 1888 | 393 | 3837 |
15 | 16 | 2852 | (1128) | 2586 | 1060 | 4847 |
25 | 7 | 3276 | (2366) | 2179 | 1360 | 8016 |
35 | 3 | 6009 | (4474) | 5287 | 1940 | 10800 |
Closest serum ferritin obtained before the start of transfusion, or closest to reference TIL value indicated (± 50 mg/kg) or LIC (± 5 mg/g dw). Serum ferritin variance was significantly greater for LICs, compared with TILs at equivalent iron load (distribution ratio F test, P < .005).
dw indicates dry liver weight.