Table 2.
Percentage of patients within given serum ferritin ranges with low, moderate, and increased iron load
| Serum ferritin, ng/mL | Transfusion iron load, mg/kg, mean percentage (SD) |
Liver iron concentration, mg/g dw, mean percentage (SD) |
||||||
|---|---|---|---|---|---|---|---|---|
| Patients/observations, n | %Less than 25 | %25 to less than 100 | %100 or more | Patients/observations, n | %Less than 2.5 | %2.5 to less than 10 | %10 or more | |
| Less than 750 | 14/24 | 51.2 (7.9) | 46.4 (8.0) | 2.4 (3.4) | 1/1 | — | 100 | 0 |
| 750 to less than 1500 | 24/50 | 4.2 | 72.9 (5.9) | 22.9 (5.9) | 8/9 | — | 75.0 | 25.0 |
| 1500 to less than 2250 | 19/51 | 0 | 29.0 (5.2) | 71.0 (5.2) | 8/10 | — | 37.5 | 62.5 |
| 2250 to less than 3000 | 13/23 | 0 | 11.5 (3.8) | 88.5 (3.8) | 9/9 | — | 22.2 | 77.8 |
| 3000 or more | 7/16 | 0 | 4.5 (6.6) | 95.5 (6.6) | 11/18 | — | 12.1(4.3) | 87.9 (4.3) |
| 1000 plus or minus 250 | 24/38 | 4.2 | 83.0 (3.9) | 12.9 (3.9) | 4/4 | — | 75.0 | 25.0 |
Averages from 1000 random data samplings (1 observation within serum ferritin range per patient selected at each sampling; same patient may be represented in > 1 serum ferritin range). All LICs in this analysis were more than 2.5 mg/g dw.
SD indicates sampling standard deviation; dw, dry liver weight; and —, not applicable.