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. 2009 Dec 1;3(12):e557. doi: 10.1371/journal.pntd.0000557

Table 1. Quantitative Trait Loci for splenomegaly, hepatomegaly, red blood cell numbers and reticulocyte percentage, that are significant (p<0.05) and highly significant (p≤0.001) in a genome-wide screen.

Phenotype Chromosome Number of marker(s)* Marker above significance threshold Significance
Spleen 1 1 TB1/1 p<0.05
2 5 TB2/16-TB2/20 p<0.05
3 9 TB3/3-TB3/10 p≤0.001
10 1 TB10/6 p<0.05
Liver 2 4 TB2/22-TB2/6 p<0.05
2 4 TB2/13-TB2/16 p<0.05
3 9 TB3/3-TB3/10 p≤0.001
4 3 TB4/16-TB4/11 p<0.05
5 2 TB5/2-TB5/1 p<0.05
6 5 TB6/2-TB6/6 p<0.05
7 2 TB7/1-Tb7/2 p<0.05
11 2 TB11/3-TB11/4 p<0.05
11 2 TB11/19-Tb11/20 p<0.05
Red blood cells 10 1 TB10/2 p<0.05
11 1 TB11/5 p<0.05
Reticulocytes 2 5 TB2/6-TB2/12 p<0.05
8 1 TB8/5 p<0.05
11 1 TB11/5 p<0.05

*Number of markers that are significant or highly significant (range of markers is indicated in brackets – for details see http://tinyurl.com/trypmap). Highly significant QTLs are shown in bold.