Table III.
All PACE patients (N = 182,116). | Patients whose primary pharmacy was among the top 5 pharmacies in Pennsylvania (N =75,413). | |||
---|---|---|---|---|
Univariate | Multivariate | Univariate | Multivariate | |
C statistic = 0.597 | C statistic = 0.599 | |||
Pseudo R2 = 0.0304 | Pseudo R2 = 0.0323 | |||
Odds ratio (95% CI) | ||||
Baseline covariates assessed in 2004 | ||||
Age, y, as of January 1, 2005 | ||||
65–74 | Reference | Reference | Reference | Reference |
75–84 | 0.96 (0.94–0.99) | 0.96 (0.94–0.99) | 0.92 (0.88–0.96) | 0.93 (0.89–0.97) |
≥85 | 1.05 (1.02–1.09) | 1.07 (1.04–1.11) | 0.90 (0.86–0.95) | 0.93 (0.88–0.98) |
Female gender | 1.06 (1.03–1.09) | 1.00 (1.00–1.00) | 1.05 (1.00–1.09) | 1.00 (1.00–1.00) |
White race | 0.64 (0.61–0.66) | 1.00 (1.00–1.00) | 0.64 (0.61–0.67) | 1.00 (1.00–1.00) |
Residence in an urban zip code | 1.27 (1.24–1.30) | 1.00 (1.00–1.00) | 1.34 (1.30–1.39) | 1.00 (1.00–1.00) |
Number of unique medications in 2004 | ||||
5 or less | Reference | Reference | Reference | Reference |
6–9 Medications | 1.29 (1.25–1.33) | 1.38 (1.34–1.43) | 1.27 (1.21–1.33) | 1.37 (1.30–1.45) |
10–14 Medications | 1.64 (1.59–1.69) | 1.83 (1.75–1.90) | 1.60 (1.52–1.68) | 1.81 (1.70–1.93) |
≥15 Medications | 2.35 (2.27–2.44) | 2.66 (2.53–2.80) | 2.38 (2.25–2.52) | 2.78 (2.57–3.01) |
Number of prescriptions filled in 2004 | ||||
<25 Prescriptions | Reference | Reference | Reference | Reference |
25–49 Prescriptions | 1.07 (1.04–1.11) | 0.87 (0.84–0.90) | 1.06 (1.01–1.12) | 0.86 (0.82–0.91) |
49–74 Prescriptions | 1.26 (1.22–1.31) | 0.82 (0.78–0.86) | 1.23 (1.16–1.30) | 0.81 (0.76–0.87) |
≥75 Prescriptions | 1.52 (1.47–1.57) | 0.77 (0.74–0.81) | 1.45 (1.37–1.53) | 0.74 (0.69–0.80) |
Charlson comorbidity index score* in 2004 | ||||
0 | Reference | Reference | Reference | Reference |
1–3 | 1.08 (1.06–1.11) | 1.07 (1.04–1.11) | 1.04 (1.00–1.08) | 1.05 (1.00–1.11) |
≥4 | 1.45 (1.41–1.50) | 1.20 (1.14–1.27) | 1.43 (1.35–1.51) | 1.18 (1.08–1.29) |
Diagnosis of cardiovascular disease in 2004 | 1.14 (1.12–1.17) | 1.00 (1.00–1.00) | 1.13 (1.09–1.17) | 1.00 (1.00–1.00) |
Diagnosis of diabetes in 2004 | 1.12 (1.09–1.15) | 1.00 (1.00–1.00) | 1.13 (1.09–1.18) | 1.00 (1.00–1.00) |
Diagnosis of psychiatric disease in 2004 | 1.34 (1.30–1.38) | 1.00 (1.00–1.00) | 1.26 (1.21–1.33) | 1.00 (1.00–1.00) |
Diagnosis of cancer (excluding nonmelanoma skin cancer) in 2004 | 1.11 (1.07–1.15) | 1.00 (1.00–1.00) | 1.12 (1.06–1.19) | 1.00 (1.00–1.00) |
The index can be used to predict 1-year mortality.