Figure 2.

Gene expression following exposure to either doxorubicin or vincristine on days 1 and 7 of cell culture. Drug exposures were performed in duplicate for both doxorubicin (100 and 500 nM) and vincristine (3 nM and 12 nM). A) Citrate synthase gene expression in Ramos cells on days 1 and 7 of cell culture following either doxorubicin or vincristine one-hour exposure. Respective dotted boxes represent percentage of viable cells recovered at each time points donated on the right Y-axis, ranging from 72%–97%. B) Isocitrate dehydrogenase expression in Ramos cells on days 1 and 7 of cell culture following either doxorubicin or vincristine one-hour exposure. C) Succinate dehydrogeanse expression in Ramos cells on days 1 and 7 of cell culture following either doxorubicin or vincristine one-hour exposure. Pair-Sample Student’s t-test used to assess significance. Error bars denote standard deviation. Colored bars indicated average of triplicate measurements. *indicates significance at the p < .05 level.