Figure 7.
Histological changes in spinal cord sections of MOG35-55-immunized AnxA1-/- mice. Haematoxylin-eosin staining of spinal cord sections obtained from AnxA1+/+ (A) and AnxA1-/- (B) mice immunized with MOG35-55 and CFA and sacrificed after 22 days. For each staining, the right panels (20×) show a higher magnification of an area of the left panels (4×). Consecutive sections were stained with anti-CD3 (C) or anti-F4/80 (D) as described in Materials and Methods. Pictures are representative of three separate experiments with similar results.