Table 3.

Summary of pharmacokinetic parameters in plasma for severe COPD patients

	Treatment	n	Mean	SD/CV
Tmax (min)	Budesonide	24	15.5*	7.2*
	Fluticasone	23	50.8*	25.4*
MRT (h)	Budesonide	24	4.41*	1.59*
	Fluticasone	23	12.78*	4.58*
Cmax (μM)	Budesonide	24	1.08†	95.9†
	Fluticasone	23	0.09†	37.9†

C_max = maximum concentration; CV = coefficient of variation; MRT = mean residence time; SD = standard deviation; T_max = time to maximum concentration.

* Arithmetic mean/SD; ^† Geometric mean/CV