Table 3.
Functional analysis for DE genes at Nfkb1-/- 180 mins from different normalization strategies
| Array-level | Strip-level | ||||
|---|---|---|---|---|---|
| Source | Term | Count | FDR | Count | FDR |
| GOTERM_BP_ALL | immune system process | 19 | 0.002 | 29 | 8.2E-5 |
| GOTERM_BP_ALL | immune response | 15 | 0.001 | 22 | 1.1E-4 |
| SP_PIR_KEYWORDS | cytokine | 9 | 0.01 | 13 | 3.3E-4 |
| GOTERM_BP_ALL | cytokine metabolic process | 4 | 0.96 | 9 | 0.005 |
| GOTERM_BP_ALL | cytokine biosynthetic process | 4 | 0.96 | 9 | 0.006 |
| INTERPRO | Fos transforming protein | 3 | 1.0 | 5 | 0.006 |
| GOTERM_BP_ALL | cytokine production | 5 | 0.88 | 10 | 0.01 |
| GOTERM_BP_ALL | leukocyte activation | 7 | 0.92 | 13 | 0.01 |
| GOTERM_BP_ALL | hemopoietic or lymphoid organ development | 7 | 0.89 | 14 | 0.01 |
| GOTERM_BP_ALL | regulation of cytokine biosynthetic process | 3 | 1.0 | 8 | 0.011 |
| GOTERM_BP_ALL | immune system development | 7 | 0.91 | 14 | 0.013 |
| GOTERM_BP_ALL | cell activation | 7 | 0.93 | 13 | 0.013 |
| GOTERM_BP_ALL | hemopoiesis | 7 | 0.94 | 13 | 0.014 |
| GOTERM_BP_ALL | positive regulation of translation | 3 | 1.0 | 7 | 0.014 |
| GOTERM_BP_ALL | positive regulation of cellular biosynthetic process | 3 | 1.0 | 7 | 0.019 |
| KEGG_PATHWAY | Cytokine-cytokine receptor interaction | 10 | 0.056 | 14 | 0.027 |
| GOTERM_MF_ALL | cytokine activity | 9 | 0.16 | 13 | 0.036 |
| SP_PIR_KEYWORDS | glycoprotein | 36 | 0.017 | 51 | 0.18 |