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. Author manuscript; available in PMC: 2010 Sep 27.
Published in final edited form as: Transplantation. 2009 Sep 27;88(6):773–781. doi: 10.1097/TP.0b013e3181b47cfa

Figure 1. Nonmyeloablative conditioning approach.

Figure 1

WF rats were conditioned with varying doses of TBI (600 to 100 cGy) on day -1, transplanted with 100 × 106 TCD ACI donor BMC on day 0, administered tacrolimus at 1 mg/kg/day (days 0-10), and a single dose of ALS on day 10. In a second experimental group, anti-αβ-TCR mAb preconditioning (on day -3) was added to the tacrolimus/ALS-based conditioning strategy.