FIG. 2.

Sohlh2-knockout anatomy and histology. A) Female reproductive tracts were dissected from 3-wk-old WT, Sohlh2^+/–, and Sohlh2^–/– mice. Note atrophic ovaries and uterine horns in the Sohlh2^–/– mice. Bar = 3 mm. B–E) Histology of 3-wk-old Sohlh2^+/–and Sohlh2^–/– ovaries. Sohlh2^–/– ovaries lack follicles, while a magnified view of the Sohlh2^+/– ovary shows well-defined primordial follicle (PF), primary follicle (PrF), and growing follicle (TF). At least five pairs of ovaries were examined, and representative sections are shown. Bar = 100 μm.