Table 1.
Biometric and spirometric characteristics of the investigated subjects
| Group A 20–29 years (n=14) | Group B 30–39 years (n=14) | Group C 40–49 years (n=14) | Group D 50–59 years (n=13) | Group E 60–69 years (n=12) | Group F > 70 years (n=13) | ANOVA/between groups | |
|---|---|---|---|---|---|---|---|
| Age (years) | 24.5+2.6 | 35.9+2.6 | 42+2.0 | 53.5+3.1 | 62.9+2.4 | 75.3+4.4 | p<0,001/A-B-C-D-E-F-A |
| Body mass (kg) | 66.9+10.9 | 62.8+10.8 | 70.9+12.8 | 67.9+11.1 | 62.9+7.6 | 63.5+9.3 | p=ns/A,B,C,D,E,F,A |
| Height (cm) | 170+10 | 166+8 | 166+9 | 164+10 | 155+6 | 159+8 | p< 0,001/A,B,C,D-E,F-A |
| BMI (kg/m2) | 22.9+2.2 | 22.6+2.4 | 25.6+2.5 | 25.0+2.4 | 25.9+2.4 | 25.1+2.5 | p<0,001/A,B-C,D,E,F-A |
| Male/Female | 7/7 | 7/7 | 7/7 | 4/9 | 2/10 | 4/9 | - |
| FEV1 (L) | 4.0±0.9 | 3.6±0.7 | 3.3±0.5 | 2.9±0.6 | 2.5±0.5 | 2.2±0.6 | p<0.001/A,B,C,D,E,F-A |
| FVC (L) | 4.6±1.2 | 4.1±0.6 | 3.9±0.6 | 3.3±0.8 | 2.9±0.5 | 2.7±0.7 | p<0.001/A,B,C,D,E,F-A |
| FEV1/FVC (%) | 87.2±5.0 | 86.8±5.8 | 84.4±4.8 | 89.3±5.5 | 86.2±5.7 | 79.9±3.3 | p<0.001/A,B,C,D,E,F-A |
| FEF/FVC (%) | 104.0±25.5 | 105.4±28.6 | 100.1±25.0 | 137.3±46.1 | 115.1±28.3 | 78.7±13.8 | p<0.001/A,B,C-D,E-F,A |
| R0 (cmH2O/L/s) | 2,5±0.7 | 2.4±0.9 | 2.8±0.7 | 3.3±1.1 | 3.4±1.1 | 2.9±1.0 | ns/A,B,C,D,E,F,A |
| S (cmH2O/L/s2) | 10.6±13.5 | −2.5±20.5 | −12.9±34.0 | −18.4±20.3 | −6.4±21.2 | −5.9±37.6 | p<0.009/A,B,C,D,E,F,A |
| Rm (cmH2O/L/s) | 2.6±0.6 | 2.4±0.8 | 2.6±0.6 | 3.1±1.0 | 3.3±1.1 | 2.8±0.8 | ns/A,B,C,D,E,F,A |
| Fr (Hz) | 11.1±2.6 | 11.7±3.3 | 14.8±4.3 | 14.5±3.6 | 15.8±4.4 | 15.6±4.9 | p<0.001/A,B-C,D,E,F-A |
| Xm (cmH2O/L/s) | 0.56±0.33 | 0.46±0.31 | 0.09±0.34 | 0.16±0.56 | 0.05±0.37 | 0.06±0.59 | p<0.001/A,B-C,D,E,F-A |
| Crs,dyn (L/cmH2O) | 0.020±0.005 | 0.021±0.005 | 0.019±0.007 | 0.016±0.006 | 0.015±0.004 | 0.016±0.007 | p<0.002/A,B,C,D,E,F-A |
n: number of subjects; Comparisons of the five groups/comparisons between groups: dashes indicate significant difference.