Table 6.

Direct drug costs

	Smart (€) n = 450	CBP (€) n = 458	p-value
Mean study drug cost per patient per 6 months	297	400	< 0.001
Mean study drug cost per patient per month	51	67	< 0.001
Mean study drug cost difference per patient per month	−15		< 0.001

CBP, conventional best practice.